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Rfam 11.0: 10 years of RNA families.

TitleRfam 11.0: 10 years of RNA families.
Publication TypeJournal Article
Year of Publication2013
AuthorsBurge SW, Daub J, Eberhardt R, Tate J, Barquist L, Nawrocki EP, Eddy SR, Gardner PP, Bateman A
JournalNucleic Acids Res
IssueDatabase issue
Date Published2013 Jan
KeywordsBase Sequence, Databases, Nucleic Acid, Genomics, Internet, Molecular Sequence Annotation, Nucleic Acid Conformation, RNA, Untranslated, Sequence Alignment, User-Computer Interface

The Rfam database (available via the website at and through our mirror at is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is represented by a multiple sequence alignment, predicted secondary structure and covariance model. Here we discuss updates to the database in the latest release, Rfam 11.0, including the introduction of genome-based alignments for large families, the introduction of the Rfam Biomart as well as other user interface improvements. Rfam is available under the Creative Commons Zero license.

Alternate JournalNucleic Acids Res.
PubMed ID23125362
PubMed Central IDPMC3531072
Grant ListWT098051 / / Wellcome Trust / United Kingdom
/ / Howard Hughes Medical Institute / United States