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A uniform system for microRNA annotation.

TitleA uniform system for microRNA annotation.
Publication TypeJournal Article
Year of Publication2003
AuthorsAmbros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T
JournalRNA
Volume9
Issue3
Pagination277-9
Date Published2003 Mar
ISSN1355-8382
KeywordsMicroRNAs, Terminology as Topic
Abstract

MicroRNAs (miRNAs) are small noncoding RNA gene products about 22 nt long that are processed by Dicer from precursors with a characteristic hairpin secondary structure. Guidelines are presented for the identification and annotation of new miRNAs from diverse organisms, particularly so that miRNAs can be reliably distinguished from other RNAs such as small interfering RNAs. We describe specific criteria for the experimental verification of miRNAs, and conventions for naming miRNAs and miRNA genes. Finally, an online clearinghouse for miRNA gene name assignments is provided by the Rfam database of RNA families.

Alternate JournalRNA
PubMed ID12592000
PubMed Central IDPMC1370393